Biochemistry

Full details for "Cholinesterase ".

Name

Cholinesterase

Alternative name/Profile

Pseudocholinesterase , CholinesteraseII

Department

Biochemistry

Investigation

Preoperative screening to detect patients with atypical forms of enzyme. Intoxication with organophosphorus compounds.

Specimen type

Serum

Sample type

Sample container & volume

5mL - Red Tube

Frequency of analysis

By prior arrangement with laboratory.

Turnaround time

1 day

Availability

By prior arrangement with laboratory.

Notes

CholinesteraseII (EC 3.1.1.7)

Serum cholinesterase serves as an indicator of possible insecticide poisoning. It is measured as an index of liver function.

In preoperative screening, cholinesterase is used to detect patients with atypical forms of the enzyme and hence avoid prolonged apnea caused by slow elimination of muscle relaxants.

Depressed cholinesterase levels are found in cases of intoxication with organophosphorus compounds and in hepatitis, cirrhosis,myocarial infarction, acute infections and atypical phenotypes of the enzyme.

Related links

Reference range

Cholinesterase Expected values:

Men: 5320 - 12920 U/L

Female Reference Range:

Age	Range (U/L)
16 - 39 (not pregnant and not using hormonal contraceptives)	4260 - 11250
18 - 41 (pregnant or taking oral contraceptives)	3650 - 9120
>40	5320 - 12920