Biochemistry
| Full details for "NT-proBNP". | |
|---|---|
Name |
NT-proBNP |
Alternative name/Profile |
BNP, N-terminal prohormone of brain natriuretic peptide, NT-pBNP |
Department |
Biochemistry |
Investigation |
Assessment of patients where a clinical diagnosis of heart failure is not definitive |
Specimen type |
Blood |
Sample type |
|
Sample container & volume |
5ml- Red Tube |
Frequency of analysis |
Daily |
Turnaround time |
1 working day / for Emergency Department and Critical Care Units turnaround time is 90 minutes |
Availability |
|
Notes |
Results are stratified based on specific age groups: <50 years, 50-70 years and >70 years. Interpret results in accordance with the appropriate clinical context e.g. acute onset or non-acute onset heart failure. Useful References: McDonagh TA, Metra M et al. European Heart Journal (2021) 42,3599-3726 Januzzi JL et al. European Heart Journal (2006) 27, 330-337
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Related links |
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Reference range |
Roche - Acute Congestive Heart Failure Acute onset HF all ages: NT-proBNP <300 pg/ml - HF unlikely Acute onset HF age <50 yrs: NT-proBNP >450 pg/mL - HF likely Acute onset HF age 50-75 yrs: NT-proBNP >900 pg/mL - HF likely Acute onset HF age >75 yrs: NTproBNP >1800 pg/mL - HF likely ESC Heart Failure guideline 2021 Non-acute onset HF: NT-proBNP <125pg/ml – HF very unlikely Non-acute onset HF: NT-proBNP ≥125pg/ml – may indicate cardiac dysfunction HSE: National Heart Programme: Heart Failure Model of Care 2021 Non-acute onset HF: NT-proBNP <400 pg/mL – HF unlikely, consider other causes Non-acute onset HF: NT-proBNP ≥ 400 pg/ml – recommend further review/investigation for HF Non-acute onset HF: NT-proBNP ≥2000 pg/mL – recommend urgent review/investigation for HF Interpret results in line with relevant clinical guidelines |
Last updated |
Mon, 30 Sep 2024 10:23:26 IST |