Biochemistry

Full details for "Calprotectin".

Name

Calprotectin

Alternative name/Profile

Calpro

Department

Biochemistry

Investigation

Faecal calprotectin is a protein found in the cytoplasm of neutrophils. Upon activation due to intestinal inflammation, cell contents are released into the stool. In clinical practice it is a useful marker of gastrointestinal inflammation, and is helpful in distinguishing between IBD and IBS, and in triaging the requirement for endoscopy

Specimen type

Random Stool Sample to be refrigerated within 1 day Faecal aspirates are not acceptable

Sample type

Sample container & volume

Universal container / 5mL

Frequency of analysis

Weekly

Turnaround time

2 Working Days

Availability

Calprotectin only available to St James Patients

Notes

Please note that results may be affected by sample quality, biological variation, and analytical factors, which can lead to minor discrepancies. A recent review in the Biochemistry Department SJH has observed an estimated result underreporting rate of approximately 2%. Thus, results should always be interpreted in the context of the patient’s clinical status at the time of sampling. If laboratory and clinical findings appear inconsistent or discordant, please contact the laboratory and submit a repeat sample promptly. Proper sample collection and handling are essential to minimise variability.

Related links

Reference range