Haematology

Full details for "Factor V Leiden mutational analysis".
Name	Factor V Leiden mutational analysis
Alternative name/Profile	Factor V Leiden mutation, Genetic tests for thrombophilia
Department	Haematology
Investigation
Specimen type	Peripheral Blood
Sample type
Sample container & volume	1 x 4ml Purple EDTA and 2 x 3ml Light Blue Tri-Sodium Citrate samples. See Notes.
Frequency of analysis	Test is performed as batch analysis. Frequency as required within turnaround time.
Turnaround time	8 weeks
Availability	Please refer to thrombophilia testing guidelines below prior to ordering this test. Routine hours Monday - Friday 9am-5pm.
Notes	Please follow links below to the specific thrombophilia request form and the guidelines for thrombophilia testing. Testing for APCR, Factor V Leiden and Prothrombin gene mutation analysis requires genetic consent. A fully completed thrombophilia request form should be sent with samples for testing. The coagulation team can be consulted for advice for thrombophilia screen requests. Samples must be received in National Coagulation Laboratory, Centre for Laboratory Medicine and Molecular Pathology, by 4pm Monday - Friday. EDTA samples from external institutions can be refrigerated and sent to the National Coagulation Laboratory within 5 days of phlebotomy. Requests for Factor V Leiden must be accompanied by either samples for APCR analysis or an APCR result from an external source. Enquiries to 01 416 2049 during routine hours, Monday - Friday 9am-5pm. This test is not generally performed during childhood unless specifically requested by a Consultant Paediatric Haematologist. The Coagulation Consultant on-call can be contacted through the hospital switchboard on 01 410 3000.
Related links	Genetic Testing for Thrombophilia - Patient Information Leaflet Thrombophilia mutation analysis consent form Thrombophilia Request Form Thrombophilia Testing Guidelines
Reference range	Factor V Leiden (1601G>A) variant analysis G/G: * VARIANT IS ABSENT * Factor V Leiden (1601G>A) variant analysis G/A: HETEROZYGOUS Factor V Leiden (1601G>A) variant analysis A/A: HOMOZYGOUS
Last updated	Wed, 26 Feb 2025 16:04:17 GMT