Haematology
| Full details for "Dapsone Screen". | |
|---|---|
Name |
Dapsone Screen |
Alternative name/Profile |
Heinz Bodies |
Department |
Haematology |
Investigation |
|
Specimen type |
Peripheral Blood |
Sample type |
|
Sample container & volume |
4ml Purple EDTA |
Frequency of analysis |
As required. |
Turnaround time |
24Hrs |
Availability |
Routine hours 9am to 5pm Monday to Friday Test available to External Hospitals. |
Notes |
Sample stability is 24 hours from collection. Purpose of Test: Heinz bodies are red blood cell inclusions which form as a result of oxidative damage to red cells, most commonly due oxidative stress, but also possibly by genetic abnormalities in haemoglobin. The presence of heinz bodies in red blood cells is an indicator that the red blood cells are being prematurely destroyed in the blood stream, and thus a sign of acute haemolysis. Heinz bodies can occur in otherwise normal red blood cells for a number of reasons: genetic conditions e.g. G6PD deficiency, NADPH deficiency, Sickle Cell Anaemia or alpha thalassaemia; from the action of chemicals or drugs, e.g. chlorates, phenyl hydrazine, primaquine, rasburicase or dapsone, and in chronic liver disease. |
Related links |
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Reference range |
Positive or negative |
Last updated |
Fri, 23 Jan 2026 15:23:44 GMT |