Haematology
| Full details for "Cyclosporine". | |
|---|---|
Name |
Cyclosporine |
Alternative name/Profile |
|
Department |
Haematology |
Investigation |
|
Specimen type |
Peripheral Blood |
Sample type |
|
Sample container & volume |
4 ml EDTA Purple |
Frequency of analysis |
Batch Analysis Twice weekly (Tuesday and Friday) |
Turnaround time |
4 working days - Urgent analysis available on request |
Availability |
Routine hours 9am to 5pm Monday to Friday. Available to internal St James's Hospital patients and External Hospitals and GPs. |
Notes |
Cyclosporin is a cyclic undecapeptide of fungal origin and a potent immunosuppressive agent. The application of therapeutic drug monitoring (TDM) and concentration-controlled dosing in order to maintain each patient’s drug exposure within a narrow therapeutic window can be achieved by measurement of pre-dose (trough level) cyclosporine concentrations. The specimen should be collected just before the next dose of cyclosporine is to be taken i.e. trough level. Limitations of this assay: Heterophilic antibodies in human serum can react with reagent immunoglobulins, interfering with in vitro immunoassays. Patients routinely exposed to animals or to animal serum products can be prone to this.
|
Related links |
|
Reference range |
Therapeutic range : 108-259ug/L |
Last updated |
Fri, 23 Jan 2026 08:29:06 GMT |