IMRL
| Full details for "Mycobacteria - Nucleic Acid Amplification Tests (NAAT)". | |
|---|---|
Name |
Mycobacteria - Nucleic Acid Amplification Tests (NAAT) |
Alternative name/Profile |
tubercle bacillus / TB / Mycobacteria tuberculosis / M. tuberculosis complex / MTC / M. africanum / M. bovis / M. bovis BCG / M. caprae / M. microti / M. canetti / M. chimaera / Non-Tuberculous Mycobacteria / NTM / M. avium-intracellulare complex ( MAC ) / M. avium / M. chelonae / M. abscessus / M. fortuitum / M.gordonae / M. intracellulare / M scrofulaceum / M interjectum / M. kansasii / M malmoense / M peregrinum / M. marinum / M. ulcerans / M. xenopi / M. simiae / M. mucogenicum / M. goodii / M. cellatum / M. smegmatis / M. genavense / M. lentiflavum / M. heckeshornense / M. szulgai / M. intermedium / M. phlei / M. hemophilum / M. gastri / M. asiaticum / M. shimoidei / tuberculin skin test / Bacillus Calmette-Guérin ( BCG ) vaccine / Mantoux test / acid fast bacillus / AFB / hazard group 3 / category 3 pathogen / Polymerase Chain Reaction / PCR / nucleic acid hybridisation / nucleic acid amplification / reverse hybridisation / Hybridization Protection Assay ( HPA ) technology / DNA strip technology / line probe assay / resistance genes / rifampicin / isoniazid / Ziehl-Neelsen stain / ZN stain / Kinyoun stain / fluorescence microscopy / auramine-rhodamine stain / Auramine O / Rhodamine B / hazard group 3 / category 3 pathogen / Mycobacterium / M. chimaera |
Department |
IMRL |
Investigation |
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Specimen type |
Refer to IMRL User Manual; specimen depends on clinical presentation. |
Sample type |
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Sample container & volume |
Sterile universal container A minimum volume of 1mL is required (0.5 ml for CSF and pleural fluids). |
Frequency of analysis |
Daily |
Turnaround time |
1 day |
Availability |
Monday - Friday |
Notes |
Rapid detection of MTC and the detection of Rifampicin resistance associated mutations can be performed directly on clinical specimens. This assay Cepheid Xpert MTB/RIF Ultra can be performed daily Monday- Friday. Please contact the IMRL before dispatching the specimen for NAAT testing. Requests for NAAT testing on smear negative specimens must be made through a Consultant Microbiologist in the Microbiology Department. A second assay for the rapid detection of MTC and its resistance to rifampicin, isoniazid, fluorquinolones and aminoglycosides can be performed on both smear positive and smear negative pulmonary specimens and cultures referred to the IMRL. This molecular assay is performed weekly on a limited basis. When a specimen is procured it must be sent to the laboratory immediately. Batching of specimens is not recommended. Should a delay be unavoidable (e.g. weekends) specimens should be refrigerated until transported |
Related links |
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Reference range |
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Last updated |
Fri, 12 Jan 2024 09:53:30 GMT |