IMRL
| Full details for "Mycobacteria - Nucleic Acid Amplification Tests (NAAT)". | |
|---|---|
Name |
Mycobacteria - Nucleic Acid Amplification Tests (NAAT) |
Alternative name/Profile |
tubercle bacillus / TB / Mycobacteria tuberculosis / M. tuberculosis complex / MTC / M. africanum / M. bovis / M. bovis BCG / M. caprae / M. microti / M. canetti / M. chimaera / Non-Tuberculous Mycobacteria / NTM / M. avium-intracellulare complex ( MAC ) / M. avium / M. chelonae / M. abscessus / M. fortuitum / M.gordonae / M. intracellulare / M scrofulaceum / M interjectum / M. kansasii / M malmoense / M peregrinum / M. marinum / M. ulcerans / M. xenopi / M. simiae / M. mucogenicum / M. goodii / M. cellatum / M. smegmatis / M. genavense / M. lentiflavum / M. heckeshornense / M. szulgai / M. intermedium / M. phlei / M. hemophilum / M. gastri / M. asiaticum / M. shimoidei / tuberculin skin test / Bacillus Calmette-Guérin ( BCG ) vaccine / Mantoux test / acid fast bacillus / AFB / hazard group 3 / category 3 pathogen / Polymerase Chain Reaction / PCR / nucleic acid hybridisation / nucleic acid amplification / reverse hybridisation / Hybridization Protection Assay ( HPA ) technology / DNA strip technology / line probe assay / resistance genes / rifampicin / isoniazid / Ziehl-Neelsen stain / ZN stain / Kinyoun stain / fluorescence microscopy / auramine-rhodamine stain / Auramine O / Rhodamine B / hazard group 3 / category 3 pathogen / Mycobacterium / M. chimaera |
Department |
IMRL |
Investigation |
|
Specimen type |
Refer to IMRL User Manual; specimen depends on clinical presentation. |
Sample type |
|
Sample container & volume |
Sterile universal container A minimum volume of 1mL is required (0.5 ml for CSF and pleural fluids). |
Frequency of analysis |
Daily |
Turnaround time |
1 day |
Availability |
Monday - Friday |
Notes |
Rapid detection of MTC and the detection of Rifampicin resistance associated mutations can be performed directly on clinical specimens. This assay Cepheid Xpert MTB/RIF Ultra can be performed daily Monday- Friday. Please contact the IMRL before dispatching the specimen for NAAT testing. Requests for NAAT testing on smear negative specimens must be made through a Consultant Microbiologist in the Microbiology Department. A reflex test for the rapid detection of resistance to isoniazid, fluoroquinolones and aminoglycosides (Cepheid Xpert MTB/XDR) will be performed where rifampicin resistance has been detected on a specimen, or where clinically relevant on a specimen or culture. Discussion with the SJH Micro Clinical team required. When a specimen is procured it must be sent to the laboratory immediately. Batching of specimens is not recommended. Should a delay be unavoidable (e.g. weekends) specimens should be refrigerated until transported |
Related links |
|
Reference range |
|
Last updated |
Thu, 23 Jan 2025 13:32:12 GMT |