Immunology

Full details for "Human Leukocyte B27".
Name	Human Leukocyte B27
Alternative name/Profile	HLA-B27, HLA B27, HLA B-27, HLAB27, Ankylosing Spondylitis, Uveitis, Juvenile Rheumatoid Arthritis, AWAY, REFER
Department	Immunology
Investigation	Next Generation Sequencing (Genotyping)
Specimen type	Blood
Sample type	EDTA (Blood)
Sample container & volume	4ml Purple EDTA
Frequency of analysis	Samples referred weekly
Turnaround time	Up to 6 weeks
Availability	*Please note this testing is available to SJH patients only* Samples are referred to The Transplantation Laboratory, Manchester Royal Infirmary, Oxford Road, Manchester.
Notes	Useful for: Investigating patients with Ankylosing Spondylitis, Juvenile Rheumatoid Arthritis, Uveitis and Retier Syndrome. Clinical Information: Approximately 8% of the normal population express the HLA-B27 antigen. Patients with rheumatic diseases such as Ankylosing Spondylitis, Juvenile Rheumatoid Arthritis, Uveitis and Reiter Syndrome have a higher prevalence of expression of HLA-B27. Although there is a higher prevalence of expression of HLA-B27 in patients with rheumatic disorders, the mechanism of disease association is unknown. Please Note: Samples for HLAB27 are referred to The Transplantation Laboratory, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL. Enquiries email judith.spencer@cmft.nhs.uk or phone 0044 161 276 6397.
Related links	Transplantation Laboratory, Manchester Royal Infirmary
Reference range	Negative Positive
Last updated	Thu, 11 Dec 2025 13:45:19 GMT