Virology
| Full details for "HIV serology". | |
|---|---|
Name |
HIV serology |
Alternative name/Profile |
HIV-I / HIV-II / HIV Antigen / HIV antibody / Human immunodeficiency virus / human T-lymphotropic virus-III / HTLV-III / lymphadenopathy-associated virus / LAV / AIDS-associated retrovirus / ARV / AIDS / Acquired Immunodeficiency Syndrome / Acquired Immune Deficiency Syndrome |
Department |
Virology |
Investigation |
|
Specimen type |
Peripheral blood |
Sample type |
|
Sample container & volume |
6 ml clotted Red top serum tube |
Frequency of analysis |
Monday - Friday |
Turnaround time |
2 days |
Availability |
Monday - Friday |
Notes |
Urgent specimens may be processed out of hours. Please contact the laboratory. Two types of human immunodeficiency viruses, collectively designated HIV, cause acquired Immunodeficiency Syndrome (AIDS). Human immunodeficiency virus type 2 (HIV-2) is similar to HIV-1 in its structural morphology, genomic organisation, and cell tropism in vitro cytopathogenicity, transmission routes and ability to cause AIDS. However HIV-2 is less pathogenic than HIV-1 and HIV-2 infections have a longer latency period with slower progression to disease, lower viral titres and lower rates of vertical and horizontal transmission. As a screening assay, this laboratory uses the Abbott Alinity HIV Ag/Ab combo assay, a two-step immunoassay, to determine the presence of HIV p24 antigen and antibodies to HIV-1 (group M and O) and HIV-2 in human serum and plasma using Chemiluminescent Microparticle Immunoassay (CMIA) technology. Reactive samples are confirmed using the bioMérieux® VIDAS HIV DUO Ultra . This HIV assay is an automated test based on the combined detection of HIV-1 p24 antigen and anti-HIV-1 and anti-HIV-2 total immunoglobulins using Enzyme Linked Fluorescence (ELFA) technology. Serotyping (HIV-1 vs. HIV-2), if required, is performed using the Bio-Rad Geenius™ HIV 1/2 Confirmatory Assay. Send sample to the laboratory without delay. Sample should be refrigerated if not transported immediately. |
Related links |
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Reference range |
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Last updated |
Thu, 04 Jul 2024 15:50:46 IST |