Cancer Molecular Diagnostics
| Full details for "GIST panel". | |
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Name |
GIST panel |
Alternative name/Profile |
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Department |
Cancer Molecular Diagnostics |
Investigation |
Prediction of response and/or resistance to targeted therapy in gastrointestinal (GI) stromal tumours |
Specimen type |
Formalin fixed paraffin embedded tissue |
Sample type |
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Sample container & volume |
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Frequency of analysis |
Weekly |
Turnaround time |
10 working days |
Availability |
Monday - Friday, 9:30am to 5pm |
Notes |
Please send a block or two 2ml clear Sarstedt screw cap micro tubes, each containing 2 scrolls x 10µm thick. The tube should be labelled with the block number. A representative H&E stained slide and histopathology report must accompany the sample. The H&E slide will be retained by the CMD laboratory. For DNA variant calling, a minimum neoplastic cell content of 10% is required. Other tests such as gene fusion detection, require a higher concentration of tumour cells. Therefore, a neoplastic cell content of > 50% is recommended where possible. If the neoplastic cell count is estimated to be <20%, mark the appropriate area on the H&E slide for macrodissection, or provide scrolls derived from a macrodissected sample. Samples for molecular testing should arrive in the laboratory as soon as possible post collection.
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Related links |
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Reference range |
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Last updated |
Tue, 17 Feb 2026 07:59:28 GMT |