Haematology
| Full details for "Heinz Bodies". | |
|---|---|
Name |
Heinz Bodies |
Alternative name/Profile |
Dapsone Screen |
Department |
Haematology |
Investigation |
|
Specimen type |
Peripheral Blood |
Sample type |
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Sample container & volume |
4ml EDTA Purple sample (or equivalent EDTA sample containers from External Hospitals acceptable also) |
Frequency of analysis |
As required. Available to External Hospitals as well as SJH patients. |
Turnaround time |
24 Hours |
Availability |
Routine hours 9am to 5pm Monday to Friday Available to |
Notes |
Sample stability is less than 24 hours post collection. Purpose of Test Heinz bodies are red blood cell inclusions which form as a result of oxidative damage to red cells, most commonly due oxidative stress, but also possibly by genetic abnormalities in haemoglobin. The presence of heinz bodies in red blood cells is an indicator that the red blood cells are being prematurely destroyed in the blood stream, and thus a sign of acute haemolysis. Heinz bodies can occur in otherwise normal red blood cells for a number of reasons: genetic conditions e.g. G6PD deficiency, NADPH deficiency, Sickle Cell Anaemia or alpha thalassaemia; from the action of chemicals or drugs, e.g. chlorates, phenyl hydrazine, primaquine, rasburicase or dapsone, and in chronic liver disease.
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Related links |
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Reference range |
Positive or negative |
Last updated |
Fri, 23 Jan 2026 16:25:59 GMT |